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Product Description
Retinol binding protein 4 (RBP4; RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
Biovision | 7566 | Human CellExp RBP4 rat recombinant DataSheet
Biomolecule/Target: RBP4
Synonyms: Retinol Binding Protein 4, Plasma retinol-binding protein, PRBP, RBP
Alternates names: Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GIF, MMIF, MIF, Glycosylation-inhibiting factor, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase.
Taglines: The primary transporter of retinol (vitamin A) to tissues and an adipokine linking GLUT4 suppression in adipose tissue to insulin
NCBI Gene ID #: 4282
NCBI Gene Symbol: MIF
Gene Source: Human
Accession #: P14174
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 97%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: <0.1 EU/g by LAL method
Activity (Specifications/test method): N/A
Biological activity: Human MIF biological activity was measured in an agarose micro droplet assay using human U937 cells as targets. The optimal range of activity found for human MIF in this assay was 0.5-1µg/ml.
Results: 0.5-1µg/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 12.5 kDa
Concentration: N/A
Appearance: Liquid
Physical form description: 0.2 m-filtered solution in PBS, pH 7.2.
Reconstitution Instructions: Reconstitute in sterile dHO to a concentration of 0.1 -1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A
