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Product Description
Tumor Necrosis Factor- (TNF-) is a highly pleiotropic cytokine with multiple activities other than its originally discovered role of tumor necrosis in rodents. It contributes to both inflammations during infections and anti-inflammatory/tissue repair processes after clearance of infection. TNF- is mainly produced by activated macrophages, T lymphocytes, and natural killer (NK) cells. The activity of TNF- is mediated through two cell surface receptors, TNF-R1 (p55) and TNF-R2 (p75) that differ in their signaling activity. TNF-'s primary role is in the regulation of immune cells. It can induce cell death of certain tumor cell lines. About 28% of cancers are susceptible to direct cell killing mediated by soluble TNF-.
Biovision | P1392 | Human CellExp TNF-alpha Extracellular Domain Human Recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2
Alternates names: E-GFP, Enhanced Green Fluorescent Protein
Taglines: A potent cytokine exerting cytotoxic effects on a wide range of cells
NCBI Gene ID #:
NCBI Gene Symbol:
Gene Source:
Accession #: P42212
Recombinant: TRUE
Source: E. coli
Purity by SDS-PAGEs:
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 32.7 kDa
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Lyophilized
Reconstitution Instructions: Reconstitute with PBS to 1 mg/ml
Amino acid sequence: N/A
