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Product Description
Tumor Necrosis Factor- (TNF-) is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells. TNF is a cytokine involved in systemic inflammation and is a member of a group of cytokines that all stimulate the acute phase reaction. TNF is mainly secreted by macrophages. TNF causes apoptotic cell death, cellular proliferation, differentiation, inflammation, tumorigenesis and viral replication, TNF is also involved in lipid metabolism, and coagulation. TNF's primary role is in the regulation of immune cells. Dysregulation and, in particular, overproduction of TNF have been implicated in a variety of human diseases- autoimmune diseases, insulin resistance, and cancer.
Biovision | 6482 | Human CellExp TNF-alpha Human Recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: Human Cellexp Human Recombinant TNF-alpha
Alternates names: RFP, Red Fluorescent Protein, R-PE, R-Phycoerythrin
Taglines: A potent lymphoid factor that exerts cytotoxic effects on a wide range of cells
NCBI Gene ID #: N/A
NCBI Gene Symbol: R-PE
Gene Source: Red algae
Accession #: N/A
Recombinant: Yes
Source: Febicos proprietary red algae
Purity by SDS-PAGEs: A566/A280 5.5
Assay: Absorbance
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per 1 g of protein
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 240 kDa
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized in PBS.
Reconstitution Instructions: Before use, centrifuge the R-PE suspension at 10,000g for 10 min at 4C. Discard the supernatant and resuspend the pellet (R-PE) into the desired buffer. R-PE is stored in a salt solution and it must be extensively dialyzed (Can use BioVisions Dialyzer tubes) or desalted in columns (BioVision Cat # 6564-25) prior to use, to remove any remaining ammonium sulphate.
Amino acid sequence: N/A
