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Product Description
Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.
Biovision | P1136 | Human CellExp TYRO3 / Dtk Human recombinant DataSheet
Biomolecule/Target: TYRO3
Synonyms: UCHL3, Ubiquitin thioesterase L3
Alternates names: TXN, TRX, TRX1
Taglines: A protein kinase superfamily member that regulates cell survival, migration and differentiation
NCBI Gene ID #: 7295
NCBI Gene Symbol: TXN
Gene Source: Human
Accession #: P10599
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per/g
Activity (Specifications/test method): N/A
Biological activity: 7-10 A650/min/mg
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 11.7 kDa (105 aa)
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Normally Trehalose is added as protectant before lyophilization.
Reconstitution Instructions: N/A
Amino acid sequence: MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT INELV
