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Product Description
LAG-1 is CC chemokine receptor (beta chemokine receptors) that signals through the CCR5 receptor. LAG-1 is identical to MIP-1 (ACT II isotype) except for two amino acid substitutions; arginine for histidine at position 22 and serine for glycine at position 47 of the mature protein. LAG-1 chemoattracts monocytes, and exhibits activity as an HIV suppressive factor. Recombinant human LAG-1 is a 7.7 kDa protein containing 69 amino acid residues.
Biovision | P1290 | LAG-1 CCL4L1 Human Recombinant DataSheet
Biomolecule/Target: LAG-1 (CCL4L1)
Synonyms: Lymphocyte Activation Gene-1, CCL4L1, ACT-2, T-cell activiation-2, HC21, C-C motif chemokine 4-like, Lymphocyte activation gene 1 protein, LAG-1, Macrophage inflammatory protein 1-beta, MIP-1-beta, Monocyte adherence-induced protein 5-alpha, Small-inducible cytokine A4-like
Alternates names: Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN- 2a.
Taglines: LAG-1 is CC chemokine that signals through the CCR5 receptor
NCBI Gene ID #: 3440
NCBI Gene Symbol: IFNA2
Gene Source: Human
Accession #: P01563
Recombinant: Yes
Source: Human 293 cell expressed
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: <0.1 EU/g
Activity (Specifications/test method): N/A
Biological activity: EDis typically 0.1 to 0.4 ng/mL. The specific activity was determined by the dose-dependent cytotoxicity of the human TF -1 cell line(human erythroleukemic indicator cell line).
Results: 0.1 to 0.4 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 16 kDa, monomer, glycosylated
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized with no additives.
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Amino acid sequence: N/A
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