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Product Description
Natural LBP is a 58KD glycoprotein produced in liver. It binds at lipid A of LPS with high affinity (10-9M) and reduced the cellular LPS effects at CD14+ cells (IL1ß, IL6, TNF). It acts as opsonin for GRAM negative cells, LPS, neutrophiles and granulocytes.
Biovision | 4936 | LBP mouse recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: LBP, recombinant LBP, recombinant lipo polysaccharide binding protein
Alternates names: Lipopolysaccharide-binding protein, LBP, LBP human recombinant protein, LBP human, human LBP
Taglines: Elicits immune responses by presenting LPS
NCBI Gene ID #: 6354
NCBI Gene Symbol: MCP3
Gene Source: Mouse
Accession #: P80098
Recombinant: Yes
Source: CHO cells
Purity by SDS-PAGEs: 99%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: <0.1 ng/g
Activity (Specifications/test method): N/A
Biological activity: The human MCP-3 produced a 10-fold increase in chemotaxis at 100 ng/ml compared to the medium control in an assay using differentiated HL-60 cells plated on a primary endothelial cell layer.
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 64.0 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2
Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1 mg/ml. This solution can be diluted into other buffered solutions or stored at 20°C for future use.
Amino acid sequence: N/A
