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Product Description
Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the bodys fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Human Leptin is a 16 kDa protein containing 146 amino acid residues.
Biovision | 4366 | Leptin human recombinant DataSheet
Biomolecule/Target: Leptin
Synonyms: OB Protein, Obesity Protein, OBS, Obesity factor.
Alternates names: Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN- 2a.
Taglines: Adipose-derived hormone which regulates energy intake & energy expenditure
NCBI Gene ID #: 3440
NCBI Gene Symbol: IFNA2
Gene Source: Human
Accession #: P01563
Recombinant: Yes
Source: Human 293 cell expressed
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: 98%
Assay #2: HPLC
Endotoxin Level: <0.1 ng/g
Activity (Specifications/test method): N/A
Biological activity: ED is typically 0.02 to 0.08 ng/mL. The specific activity was determined by the dose-dependent cytotoxicity of the human TF -1 cell line(human erythroleukemic indicator cell line).
Results: 0.02 to 0.08 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 16 kDa, monomer, glycosylated
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Sterile filtered and lyophilized
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Amino acid sequence: N/A
