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Product Description
Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the bodys fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Murine Leptin is a 16 kDa protein containing 147 amino acid residues.
Biovision | 4367 | Leptin murine recombinant DataSheet
Biomolecule/Target: Leptin
Synonyms: OB Protein, Obesity Protein, OBS, Obesity factor.
Alternates names: Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF), IL1F2, IL-1 beta.
Taglines: Adipose-derived hormone which regulates energy intake & energy expenditure
NCBI Gene ID #: 3553
NCBI Gene Symbol: IL1B
Gene Source: Human
Accession #: P01584
Recombinant: Yes
Source: Human 293 cell expressed
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: N/A
Assay #2: HPLC
Endotoxin Level: <0.1 ng/g
Activity (Specifications/test method): N/A
Biological activity: ED is typically 0.02 to 0.08 ng/mL. The specific activity was determined by the dose-dependent stimulation of the proliferation of mouse D10S cells.
Results: 0.02 to 0.08 ng/ml
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 18 and 25 kDa, monomer, glycosylated
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized with no additives
Reconstitution Instructions: Reconstitute in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.
Amino acid sequence: N/A
