Tumor necrosis factor ligand superfamily member 11 (TNFSF11), also known as Receptor Activator of Nuclear factor Kappa-B Ligand (RANKL), is a member of the tumor necrosis factor (TNF) ligand family. RANKL regulates bone remodeling and the development
Source:
Yeast
Gene name:
Tnfsf11
Contents:
Lyophilized without carrier protein.
Form:
Lyophilized
Purification:
Ion-exchange chromatography.
Storage:
Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when
stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Isoform 1: Cell membrane; Single-pass type II membrane protein.
Tissue specificity:
Highly expressed in thymus and lymph nodes, but not in non-lymphoid tissues and is abundantly expressed in T- cells but not in B-cells. A high level expression is also seen in the trabecular bone and lung.
BackgroundTumor necrosis factor ligand superfamily member 11 (TNFSF11), also known as Receptor Activator of Nuclear factor Kappa-B Ligand (RANKL), is a member of the tumor necrosis factor (TNF) ligand family. RANKL regulates bone remodeling and the development
SourceYeast
Gene nameTnfsf11
ContentsLyophilized without carrier protein.
FormLyophilized
PurificationIon-exchange chromatography.
StorageStable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when
stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Subcellular localizationIsoform 1: Cell membrane; Single-pass type II membrane protein.
Tissue specificityHighly expressed in thymus and lymph nodes, but not in non-lymphoid tissues and is abundantly expressed in T- cells but not in B-cells. A high level expression is also seen in the trabecular bone and lung.
Uniprot IDO35235
Other Size5μg/vial, Please contact us for more details