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Product Description
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by activated T cells, monocytes and Kaposis sarcoma cells, OSM can exert both stimulatory and inhibitory effects on cell proliferation. It stimulates the proliferation of fibroblasts, smooth muscle cells and Kaposis sarcoma cells, but, inhibits the growth of some normal and tumor cell lines. It also promotes cytokine release (e.g. IL-6, GM-CSF and G-CSF) from endothelial cells, and enhances the expression of low-density lipoprotein receptor in hepatoma cells. OSM share several structural and functional characteristics with LIF, IL-6, and CNTF. Human OSM is active on murine cells. Recombinant rat Oncostatin M is a 24.4 kDa protein, containing 215 amino acid residues.
Biovision | 7182 | Oncostatin M rat recombinant DataSheet
Biomolecule/Target: Oncostatin M
Synonyms: OSM
Alternates names: Protein A/G/L
Taglines: Participates in the regulation of neurogenesis, osteogenesis and hematopoiesis.
NCBI Gene ID #: N/A
NCBI Gene Symbol: N/A
Gene Source: N/A
Accession #: N/A
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: 95%
Assay #2: HPLC
Endotoxin Level: <0.1 ng/g
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 101.0 kDa
Concentration: N/A
Appearance: Lyophilized powder
Physical form description: Lyophilized with no additives
Reconstitution Instructions: Reconstitution in HO to a concentration of 10 mg/ml gives a clear solution.
Amino acid sequence: N/A
