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Product Description
PTEN Human, Phosphatase and Tensin homolog Human Recombinant Protein, His Tag
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Background PTEN Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 423 amino acids (1- 403 a.a.) and having a molecular mass of 49.3kDa.
The PTEN is purified by pr
The PTEN is purified by pr
Source E. Coli
Gene name PTEN
Contents The PTEN solution contains 20mM Tris-HCl buffer (pH 8.0), 1mM EDTA, 2mM DTT, 100mM NaCl, and 20% glycerol.
Form Sterile Filtered colorless solution.
Purification Greater than 85.0% as determined by SDS-PAGE.
Storage Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Application Cell Culture
Synonyms Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN;3.1.3.16;3.1.3.48;3.1.3.67;Mutated in multiple advanced cancers 1;Phosphatase and tensin homolog;PTEN;MMAC1, TEP1;
Subcellular localization Cytoplasm. Nucleus. Nucleus, PML body. Monoubiquitinated form is nuclear. Nonubiquitinated form is cytoplasmic. Colocalized with PML and USP7 in PML nuclear bodies. XIAP/BIRC4 promotes its nuclear localization.
Tissue specificity Expressed at a relatively high level in all adult tissues, including heart, brain, placenta, lung, liver, muscle, kidney and pancreas.
Uniprot ID P60484
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