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Product Description
Recombinant Human p16-INK4a Protein
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Background p16-INK4a is a nuclear protein that regulates the cell cycle by inhibiting cyclin dependent kinase-4 (CDK4) and CDK6. p16-INK4a inhibits CDK activity by binding to the CDK molecules in a manner that interferes with their ability to interact with cycl
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>Kim, W.Y. and Sharpless, N.E. (2006) <em>Cell</em> <strong>127</strong>(2):265-75.</span><a href http://www.ncbi.nlm.nih.gov/pubmed?term=Sharpless%20NE%5BAuthor%5D&
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Source E. Coli
Gene name CDKN2A
Contents Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
Form Solid; white powder or thin/invisible film
Purification N/A
Storage Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Application Cell Culture
Synonyms Cyclin-dependent kinase inhibitor 2A ;Cyclin-dependent kinase 4 inhibitor A;CDK4I;Multiple tumor suppressor 1;MTS-1;p16-INK4a;p16-INK4;p16INK4A;CDKN2A ;CDKN2, MTS1; Cyclin-dependent kinase inhibitor 2A, Cyclin-dependent kinase 4 inhibitor A, CDK4I, p
Subcellular localization Cytoplasm . Nucleus .
Tissue specificity Widely expressed but not detected in brain or skeletal muscle. Isoform 3 is pancreas-specific. .
Uniprot ID P42771
Other Size Various Sizes, Please contact us for more details
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