TWEAKR belongs to the TNF family of transmembrane proteins and contains a cytoplasmic death domain", which can activated the cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine.
Source:
E. Coli
Gene name:
TNFRSF12A
Contents:
Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
Form:
Solid; white powder or thin/invisible film
Purification:
N/A
Storage:
Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Application:
Cell Culture
Synonyms:
Tumor necrosis factor receptor superfamily member 12A;Fibroblast growth factor-inducible immediate-early response protein 14;FGF-inducible 14;Tweak-receptor;TweakR;CD266;TNFRSF12A;FN14; TNF-related weak inducer of apoptosis receptor, TNFRSF12A, FGF-i
Subcellular localization:
Membrane; Single-pass type I membrane protein.
Tissue specificity:
Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
BackgroundTWEAKR belongs to the TNF family of transmembrane proteins and contains a cytoplasmic death domain", which can activated the cell's apoptotic machinery. It is expressed in the spleen, thymus, peripheral blood lymphocytes, colon, and small intestine.
SourceE. Coli
Gene nameTNFRSF12A
ContentsProtein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
FormSolid; white powder or thin/invisible film
PurificationN/A
StorageStore in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
ApplicationCell Culture
SynonymsTumor necrosis factor receptor superfamily member 12A;Fibroblast growth factor-inducible immediate-early response protein 14;FGF-inducible 14;Tweak-receptor;TweakR;CD266;TNFRSF12A;FN14; TNF-related weak inducer of apoptosis receptor, TNFRSF12A, FGF-i
Subcellular localizationMembrane; Single-pass type I membrane protein.
Tissue specificityHighly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Uniprot IDQ9NP84
Other SizeVarious Sizes, Please contact us for more details