PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including s
Source:
E. Coli
Gene name:
Pdgfb
Contents:
Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
Form:
Solid; white powder or thin/invisible film
Purification:
N/A
Storage:
Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Localized to vascular smooth muscle cells. Also weakly expressed by cortical interstitial cells but absent in tubules. Up-regulated in areas of renal fibrosis. In mice with unilateral ureteral obstruction, an increased expression in interstitial cell
BackgroundPDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including s
SourceE. Coli
Gene namePdgfb
ContentsProtein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
FormSolid; white powder or thin/invisible film
PurificationN/A
StorageStore in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Subcellular localizationSecreted. Released by platelets upon wounding. .
Tissue specificityLocalized to vascular smooth muscle cells. Also weakly expressed by cortical interstitial cells but absent in tubules. Up-regulated in areas of renal fibrosis. In mice with unilateral ureteral obstruction, an increased expression in interstitial cell
Uniprot IDP31240
Other SizeVarious Sizes, Please contact us for more details