RELMβ (Resistin-like molecule β/FIZZ2) is an 18 kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELMβ, and its molecular targets, are not fully known but,
Source:
E. Coli
Gene name:
Retnlb
Contents:
Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
Form:
Solid; white powder or thin/invisible film
Purification:
N/A
Storage:
Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Application:
Cell Culture
Synonyms:
Resistin-like beta;Cysteine-rich secreted protein A12-beta;Cysteine-rich secreted protein FIZZ2;RELMbeta;Retnlb;Fizz2; Resistin-like β, Cysteine-rich secreted protein FIZZ2
Subcellular localization:
Secreted .
Tissue specificity:
Strongly expressed in colon, and at lower levels in ileum (PubMed:15834545). In colon, found throughout the crypt and surface epithelium and in goblet cells (at protein level) (PubMed:15834545). Specific to the gastrointestinal tract; not detected in
BackgroundRELMβ (Resistin-like molecule β/FIZZ2) is an 18 kDa disulfide-linked homodimeric protein expressed in the epithelium of the colon and small bowel. The biological functions of RELMβ, and its molecular targets, are not fully known but,
SourceE. Coli
Gene nameRetnlb
ContentsProtein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
FormSolid; white powder or thin/invisible film
PurificationN/A
StorageStore in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
ApplicationCell Culture
SynonymsResistin-like beta;Cysteine-rich secreted protein A12-beta;Cysteine-rich secreted protein FIZZ2;RELMbeta;Retnlb;Fizz2; Resistin-like β, Cysteine-rich secreted protein FIZZ2
Subcellular localizationSecreted .
Tissue specificityStrongly expressed in colon, and at lower levels in ileum (PubMed:15834545). In colon, found throughout the crypt and surface epithelium and in goblet cells (at protein level) (PubMed:15834545). Specific to the gastrointestinal tract; not detected in
Uniprot IDQ99P86
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