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Product Description
Recombinant Murine Sonic Hedgehog (Shh) Protein
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Size 25ug
Background Members of the Hedgehog (Hh) family are highly conserved proteins which are widely represented throughout the animal kingdom. The three known mammalian Hh proteins, Sonic (Shh), Desert (Dhh) and Indian (Ihh) are structurally related and share a hig
Source E. Coli
Gene name Shh
Contents Protein concentration verified by UV Spectroscopy and/or SDS-PAGE gel.
Form Solid; white powder or thin/invisible film
Purification N/A
Storage Store in -20°C for long term storage. After reconstitution, store in 4°C for short term usage within a few days. Avoid freeze-thaw cycles.
Application Cell Culture
Synonyms Sonic hedgehog protein;SHH;HHG-1;Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains ;ShhNC ;Sonic hedgehog protein N-product;ShhN;Shh N-terminal processed signaling domains ;ShhNp ;Sonic hedgehog protein 19 kDa product;Shh ;Hh
Subcellular localization Sonic hedgehog protein N-product: Cell membrane ; Lipid-anchor . The dual-lipidated sonic hedgehog protein N-product (ShhNp) is firmly tethered to the cell membrane where it forms multimers (PubMed:24522195). Further solubilization and release from t
Tissue specificity Expressed in a number of embryonic tissues including the notochord, ventral neural tube, floor plate, lung bud, zone of polarizing activity and posterior distal mesenchyme of limbs. In the adult, expressed in lung and neural retina.
Uniprot ID Q62226
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