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![Recombinant Human IL-24 Protein [CHO cells]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/671474/929317/logo__42078.1651665136__42998.1651684287.jpg?c=2 "Recombinant Human IL-24 Protein [CHO cells]"){kind=logo}
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Product Description
Recombinant Human IL-24 Protein [CHO cells] | 100-104S/100-104 | ReliaTech
Species: Human
Host / biotech: CHO cells
Comment: N/A
Label: His-tag
Clone / Antibody feature: N/A
Subcategory: Cytokines & Growth Factors
Category: Recombinant Protein
Synonyms: interleukin 24; C49A; FISP; MDA7; MOB5; ST16; IL10B
Isotype: N/A
Application: N/A
Detection Range: Testing in progress.
Species Reactivity/Cross reactivity: Human
Antigen: N/A
Description: IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.
Purity Confirmation: > 95% by SDS-PAGE & HPLC analyses
Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
Formulation: lyophilized
Storage Handling Stability: N/A
Reconstituation: N/A
Molecular Weight: 18.9 kDa
Lenght (aa): 161
Protein Sequence: QEFHFGPCQV KGVVPQKLWE AFWAVKDTMQ AQDNITSARL LQQEVLQNVS DAESCYLVHT LLEFYLKTVF KNYHNRTVEV RTLKSFSTLA NNFVLIVSQL QPSQENEMFS IRDSAHRRFL LFRRAFKQLD VEAALTKALG EVDILLTWMQ KFYKLHHHHH H
NCBI Gene ID: 11009
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