Euro
USD
British Pound
NULL
![Recombinant Human IL-36 beta (IL-1F8) Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/671488/929331/logo__42078.1651665136__78802.1651684292.jpg?c=2 "Recombinant Human IL-36 beta (IL-1F8) Protein [E. coli]"){kind=logo}
![Recombinant Human IL-36 beta (IL-1F8) Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/671488/929331/logo__42078.1651665136__78802.1651684292.jpg?c=2 "Recombinant Human IL-36 beta (IL-1F8) Protein [E. coli]"){kind=logo}
Product Description
Recombinant Human IL-36 beta (IL-1F8) Protein [E. coli] | 100-091S/100-091 | ReliaTech
Species: Human
Host / biotech: E. coli
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Cytokines & Growth Factors
Category: Recombinant Protein
Synonyms: FIL1; FIL1H; IL1F8; IL1H2; IL-1F8; IL-1H2; IL1-ETA; FIL1- (ETA); FILI- (ETA)
Isotype: N/A
Application: N/A
Detection Range: Measured by its ability to induce IL-8 production by human PBMCs.
Species Reactivity/Cross reactivity: Human
Antigen: N/A
Description: The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36β is highly expressed in psoriatic plaques, and at lower levels in various other tissues. IL-36β signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36β also functions as an agonist of NF-kappaB, and stimulates the production of pro-inflammatory proteins, including IL-6, IL-8, BD-2, and BD-3. Recombinant human IL-36β is a 17.3 kDa protein containing 154 amino acid residues.
Purity Confirmation: > 98% by SDS-PAGE & HPLC analyses
Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
Formulation: lyophilized
Storage Handling Stability: N/A
Reconstituation: N/A
Molecular Weight: 17.3 kDa
Lenght (aa): 154
Protein Sequence: MREAAPKSYA IRDSRQMVWV LSGNSLIAAP LSRSIKPVTL HLIACRDTEF SDKEKGNMVY LGIKGKDLCL FCAEIQGKPT LQLKEKNIMD LYVEKKAQKP FLFFHNKEGS TSVFQSVSYP GWFIATSTTS GQPIFLTKER GITNNTNFYL DSVE
NCBI Gene ID: 27177
![Recombinant Human IL-36 beta (IL-1F8) Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671488/929331/logo__42078.1651665136__78802.1651684292.jpg?c=2 "Recombinant Human IL-36 beta (IL-1F8) Protein [E. coli]"){kind=logo}
![Recombinant Human IL-36 alpha (IL-1F6) Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671487/929330/logo__42078.1651665136__23053.1651684292.jpg?c=2 "Recombinant Human IL-36 alpha (IL-1F6) Protein [E. coli]"){kind=logo}
![Recombinant Human IL-36 gamma (IL-1F9) Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671489/929332/logo__42078.1651665136__10712.1651684293.jpg?c=2 "Recombinant Human IL-36 gamma (IL-1F9) Protein [E. coli]"){kind=logo}
![Recombinant Human IL-37 (IL-1F7) Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671491/929334/logo__42078.1651665136__96075.1651684294.jpg?c=2 "Recombinant Human IL-37 (IL-1F7) Protein [E. coli]"){kind=logo}
![Recombinant Human IL-17E Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671434/929277/logo__42078.1651665136__23219.1651684277.jpg?c=2 "Recombinant Human IL-17E Protein [E. coli]"){kind=logo}