Euro
USD
British Pound
NULL
![Recombinant Human MMP-1 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/671714/929557/logo__42078.1651665136__96755.1651684358.jpg?c=2 "Recombinant Human MMP-1 Protein [E. coli]"){kind=logo}
![Recombinant Human MMP-1 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/671714/929557/logo__42078.1651665136__96755.1651684358.jpg?c=2 "Recombinant Human MMP-1 Protein [E. coli]"){kind=logo}
Product Description
Recombinant Human MMP-1 Protein [E. coli] | 100-419S/100-419 | ReliaTech
Species: Human
Host / biotech: E. coli
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Cytokines & Growth Factors
Category: Recombinant Protein
Synonyms: Matrix metalloproteinase-1, fibroblast collagenase, interstitial collagenase
Isotype: N/A
Application: N/A
Detection Range: MMP-1 activity was measured by its ability to cleave a chromogenic peptide MMP-1 substrate at room temperature. At an MMP-1 concentration of 2.5 μg/ml, 50% cleavage was achieved at an incubation time of approximately 25 minutes
Species Reactivity/Cross reactivity: Human
Antigen: N/A
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-1 is a secreted collagenase with specificity toward Type I, II, III, VII, and X collagens. Recombinant human MMP-1 is a 42.7 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain which is involved in substrate specificity and in binding TIMP-1.
Purity Confirmation: > 90% by SDS-PAGE & HPLC analysis
Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
Formulation: lyophilized
Storage Handling Stability: N/A
Reconstituation: N/A
Molecular Weight: 42.7 kDa
Lenght (aa): 371
Protein Sequence: MFVLTEGNPR WEQTHLTYRI ENYTPDLPRA DVDHAIEKAF QLWSNVTPLT FTKVSEGQAD IMISFVRGDH RDNSPFDGPG GNLAHAFQPG PGIGGDAHFD EDERWTNNFR EYNLHRVAAH ELGHSLGLSH STDIGALMYP SYTFSGDVQL AQDDIDGIQA IYGRSQNPVQ PIGPQTPKAC DSKLTFDAIT TIRGEVMFFK DRFYMRTNPF YPEVELNFIS VFWPQLPNGL EAAYEFADRD EVRFFKGNKY WAVQGQNVLH GYPKDIYSSF GFPRTVKHID AALSEENTGK TYFFVANKYW RYDEYKRSMD PGYPKMIAHD FPGIGHKVDA VFMKDGFFYF FHGTRQYKFD PKTKRILTLQ KANSWFNCRK N
NCBI Gene ID: 4312
![Recombinant Human MMP-1 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671714/929557/logo__42078.1651665136__96755.1651684358.jpg?c=2 "Recombinant Human MMP-1 Protein [E. coli]"){kind=logo}
![Recombinant Human MMP-3 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671719/929562/logo__42078.1651665136__28770.1651684359.jpg?c=2 "Recombinant Human MMP-3 Protein [E. coli]"){kind=logo}
![Recombinant Human MMP-2 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671715/929558/logo__42078.1651665136__64400.1651684358.jpg?c=2 "Recombinant Human MMP-2 Protein [E. coli]"){kind=logo}
![Recombinant Human SDF-1 beta (CXCL12) Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671978/929821/logo__42078.1651665136__65615.1651684438.jpg?c=2 "Recombinant Human SDF-1 beta (CXCL12) Protein [E. coli]"){kind=logo}
![Recombinant Human TIMP-1 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672097/929940/logo__42078.1651665136__09679.1651684475.jpg?c=2 "Recombinant Human TIMP-1 Protein [E. coli]"){kind=logo}
![Recombinant Human IGF-1 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671215/929058/logo__42078.1651665136__69128.1651684210.jpg?c=2 "Recombinant Human IGF-1 Protein [E. coli]"){kind=logo}
![Recombinant Human WISP-1 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672331/930174/logo__42078.1651665136__68116.1651684553.jpg?c=2 "Recombinant Human WISP-1 Protein [E. coli]"){kind=logo}
![Recombinant Human Galectin-1 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671068/928911/logo__42078.1651665136__41170.1651684167.jpg?c=2 "Recombinant Human Galectin-1 Protein [E. coli]"){kind=logo}
![Recombinant Human PAI-1 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671816/929659/logo__42078.1651665136__17565.1651684386.jpg?c=2 "Recombinant Human PAI-1 Protein [E. coli]"){kind=logo}
![Recombinant Human GLP-1 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671117/928960/logo__42078.1651665136__44480.1651684181.jpg?c=2 "Recombinant Human GLP-1 Protein [E. coli]"){kind=logo}