Euro
USD
British Pound
NULL
![Recombinant Human VEGF-D Protein [HEK 293 cells]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/672266/930109/logo__42078.1651665136__28359.1651684529.jpg?c=2 "Recombinant Human VEGF-D Protein [HEK 293 cells]"){kind=logo}
![Recombinant Human VEGF-D Protein [HEK 293 cells]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/672266/930109/logo__42078.1651665136__28359.1651684529.jpg?c=2 "Recombinant Human VEGF-D Protein [HEK 293 cells]"){kind=logo}
Product Description
Recombinant Human VEGF-D Protein [HEK 293 cells] | 100-374S/100-374 | ReliaTech
Species: Human
Host / biotech: HEK 293 cells
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Cytokines & Growth Factors
Category: Recombinant Protein
Synonyms: vascular endothelial growth factor D; FIGF; VEGFD; VEGF-D
Isotype: N/A
Application: N/A
Detection Range: Measured by its ability to bind recombinant human VEGFR3/Flt-4 Fc in a functional ELISA.
Species Reactivity/Cross reactivity: Human
Antigen: N/A
Description: VEGF-D, a member of the VEGF/PDGF family of structurally related proteins, is a potent angiogenic cytokine. It promotes endothelial cell growth, promotes lymph angiogenesis, and can also affect vascular permeability. VEGF-D is highly expressed in the lung, heart, small intestine and fetal lung, and at lower levels in the skeletal muscle, colon, and pancreas. It forms cell surfaced-associated non-covalent disulfide linked homodimers, and can bind and activate both VEGFR-2 (flk1) and VEGFR-3 (flt4) receptors. During embryogenesis, VEGF-D may play a role in the formation of the venous and lymphatic vascular systems. It also participates in the growth and maintenance of differentiated lymphatic endothelium in adults. Both VEGF-C and VEGF-D are over-expressed in certain cancers, and the resulting elevated levels of VEGF-C or VEGF-D tend to correlate with increased lymphatic metastasis. Recombinant human VEGF-D is a 13.1 kDa non-disulfide linked homodimeric protein consisting of two 117 amino acid polypeptide chains. Due to glycosylation the protein migrates as a 20.0-22.0 kDa band under non-reducing condition.
Purity Confirmation: > 95% by SDS-PAGE & HPLC analyses
Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
Formulation: lyophilized
Storage Handling Stability: N/A
Reconstituation: N/A
Molecular Weight: 26.2 kDa
Lenght (aa): 117
Protein Sequence: FAATFYDIET LKVIDEEWQR TQCSPRETCV EVASELGKST NTFFKPPCVN VFRCGGCCNE ESLICMNTST SYISKQLFEI SVPLTSVPEL VPVKVANHTG CKCLPTAPRH PYSIIRR
NCBI Gene ID: 2277
![Recombinant Human VEGF-D Protein [HEK 293 cells]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672266/930109/logo__42078.1651665136__28359.1651684529.jpg?c=2 "Recombinant Human VEGF-D Protein [HEK 293 cells]"){kind=logo}
![Recombinant Human NOGGIN Protein [HEK 293 cells]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671773/929616/logo__42078.1651665136__58650.1651684373.jpg?c=2 "Recombinant Human NOGGIN Protein [HEK 293 cells]"){kind=logo}
![Recombinant Human Vitronectin Protein [HEK 293 cells]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672325/930168/logo__42078.1651665136__07041.1651684552.jpg?c=2 "Recombinant Human Vitronectin Protein [HEK 293 cells]"){kind=logo}
![Recombinant Human Osteopontin Protein [HEK 293 cells]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671807/929650/logo__42078.1651665136__30830.1651684382.jpg?c=2 "Recombinant Human Osteopontin Protein [HEK 293 cells]"){kind=logo}
![Recombinant Human KLF4-TAT Protein [HEK 293 cells]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671541/929384/logo__42078.1651665136__71181.1651684305.jpg?c=2 "Recombinant Human KLF4-TAT Protein [HEK 293 cells]"){kind=logo}
![Recombinant Human TLR-3 Protein [HEK 293 cells]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672105/929948/logo__42078.1651665136__12044.1651684478.jpg?c=2 "Recombinant Human TLR-3 Protein [HEK 293 cells]"){kind=logo}