Euro
USD
British Pound
NULL
![Recombinant Mouse APRIL Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/670469/928312/logo__42078.1651665136__11401.1651683808.jpg?c=2 "Recombinant Mouse APRIL Protein [E. coli]"){kind=logo}
![Recombinant Mouse APRIL Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/670469/928312/logo__42078.1651665136__11401.1651683808.jpg?c=2 "Recombinant Mouse APRIL Protein [E. coli]"){kind=logo}
Product Description
Recombinant Mouse APRIL Protein [E. coli] | M10-050S/M10-050 | ReliaTech
Species: Mouse
Host / biotech: E. coli
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Cytokines & Growth Factors
Category: Recombinant Protein
Synonyms: Tnfsf13; April; Tall2; Trdl1; 2310026N09Rik
Isotype: N/A
Application: N/A
Detection Range: Measured by its ability to induce cell proliferation of activated T cells.
Species Reactivity/Cross reactivity: Human, Mouse
Antigen: N/A
Description: APRIL (a proliferation inducing ligand), also known as TNFSF13, TALL2, and TRDL1, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa type II transmembrane protein which is cleaved by furin in the Golgi to release a 17 kDa soluble molecule. Secreted APRIL consists almost entirely of a single TNF homology domain. Little or no transmembrane APRIL is expressed on the cell surface. Alternate splicing generates isoforms with short deletions at the Nor C-terminus. Both APRIL and the closely related protein BAFF signal through the TNF superfamily receptors TACI and BCMA to promote cellular proliferation and protect from apoptosis. APRIL can form bioactive heterotrimers with BAFF. A bioactive cell surface-expressed protein known as TWEPRIL consists of the intracellular domain, transmembrane segment, and stalk region of TWEAK fused to the TNF homology domain of APRIL. Human APRIL shares 85% amino acid sequence identity with mouse and rat APRIL.
Purity Confirmation: > 98% by SDS-PAGE & HPLC analyses
Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
Formulation: lyophilized
Storage Handling Stability: N/A
Reconstituation: N/A
Molecular Weight: 21.9 kDa
Lenght (aa): 192
Protein Sequence: MRREVSRLQR SGGPSQKQGE RPWQSLWEQS PDVLEAWKDG AKSRRRRAVL TQKHKKKHSV LHLVPVNITS KDSDVTEVMW QPVLRRGRGL EAQGDIVRVW DTGIYLLYSQ VLFHDVTFTM GQVVSREGQG RRETLFRCIR SMPSDPDRAY NSCYSAGVFH LHQGDIITVK IPRANAKLSL SPHGTFLGFV KL
NCBI Gene ID: 69583
![Recombinant Mouse APRIL Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670469/928312/logo__42078.1651665136__11401.1651683808.jpg?c=2 "Recombinant Mouse APRIL Protein [E. coli]"){kind=logo}
![Recombinant Mouse TPO Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672172/930015/logo__42078.1651665136__18572.1651684492.jpg?c=2 "Recombinant Mouse TPO Protein [E. coli]"){kind=logo}
![Recombinant Mouse TRAIL Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672176/930019/logo__42078.1651665136__17118.1651684493.jpg?c=2 "Recombinant Mouse TRAIL Protein [E. coli]"){kind=logo}
![Recombinant Mouse Leptin Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671563/929406/logo__42078.1651665136__13644.1651684311.jpg?c=2 "Recombinant Mouse Leptin Protein [E. coli]"){kind=logo}
![Recombinant Mouse GPR15L Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671134/928977/logo__42078.1651665136__19885.1651684187.jpg?c=2 "Recombinant Mouse GPR15L Protein [E. coli]"){kind=logo}
![Recombinant Mouse Amphiregulin Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670445/928288/logo__42078.1651665136__44649.1651683802.jpg?c=2 "Recombinant Mouse Amphiregulin Protein [E. coli]"){kind=logo}