Euro
USD
British Pound
NULL
![Recombinant Mouse GPR15L Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/671134/928977/logo__42078.1651665136__19885.1651684187.jpg?c=2 "Recombinant Mouse GPR15L Protein [E. coli]"){kind=logo}
![Recombinant Mouse GPR15L Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/671134/928977/logo__42078.1651665136__19885.1651684187.jpg?c=2 "Recombinant Mouse GPR15L Protein [E. coli]"){kind=logo}
Product Description
Recombinant Mouse GPR15L Protein [E. coli] | M10-144S/M10-144 | ReliaTech
Species: Mouse
Host / biotech: E. coli
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Cytokines & Growth Factors
Category: Recombinant Protein
Synonyms: secreted protein C10orf99 homolog, RIKEN cDNA 2610528A11 gene, AW494830
Isotype: N/A
Application: N/A
Detection Range: Product in testing.
Species Reactivity/Cross reactivity: N/A
Antigen: N/A
Description: GPR15L is a newly identified ligand for GPR15, a member of the G protein‐coupled receptor (GPCR) family. Upon ligation, GPR15L acts as a potent chemoattractant for GPR15‐expressing T cells and together they mediate lymphocyte recruitment to the large intestine and skin. GPR15L is constitutively expressed by colon epithelial cells where its expression is minimally altered by intestinal inflammation. Conversely, GPR15L is nearly undetectable in adult epidermis but highly upregulated during wound healing and inflammation, particularly in psoriasis. Significant expression of GPR15L is also seen in additional mucosal epithelial cells, including those of the stomach, esophagus, and urinary tract. While maintaining similar expression patterns and intramolecular disulfide cysteine bridges found in members of the CC chemokine family, GPR15L differs from classic CC and CXC chemokines, whose active sites are found on the N‐terminus, in that it relies on its C‐terminus for receptor interaction. GPR15L was first identified as an antimicrobial peptide (AMP) due to its broad spectrum of antimicrobial activity, a property shared with many chemokines. GPR15L binds to an additional receptor, SUSD2, and early studies have indicated that both are downregulated in colon cancer tissue resulting in inhibited colon cancer growth.
Purity Confirmation: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
Formulation: lyophilized
Storage Handling Stability: N/A
Reconstituation: N/A
Molecular Weight: 6.3 kDa
Lenght (aa): 54
Protein Sequence: RRHPAKSLKL RRCCHLSPRS KLTTWKGNHT RPCRLCRNKL PVKSWVVPGA LPQI
NCBI Gene ID: 70045
![Recombinant Mouse GPR15L Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671134/928977/logo__42078.1651665136__19885.1651684187.jpg?c=2 "Recombinant Mouse GPR15L Protein [E. coli]"){kind=logo}
![Recombinant Mouse Amphiregulin Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670445/928288/logo__42078.1651665136__44649.1651683802.jpg?c=2 "Recombinant Mouse Amphiregulin Protein [E. coli]"){kind=logo}
![Recombinant Mouse APRIL Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670469/928312/logo__42078.1651665136__11401.1651683808.jpg?c=2 "Recombinant Mouse APRIL Protein [E. coli]"){kind=logo}
![Recombinant Mouse C5a Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670552/928395/logo__42078.1651665136__86313.1651684033.jpg?c=2 "Recombinant Mouse C5a Protein [E. coli]"){kind=logo}
![Recombinant Mouse TPO Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672172/930015/logo__42078.1651665136__18572.1651684492.jpg?c=2 "Recombinant Mouse TPO Protein [E. coli]"){kind=logo}
![Recombinant Mouse TRAIL Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672176/930019/logo__42078.1651665136__17118.1651684493.jpg?c=2 "Recombinant Mouse TRAIL Protein [E. coli]"){kind=logo}
![Recombinant Mouse Leptin Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671563/929406/logo__42078.1651665136__13644.1651684311.jpg?c=2 "Recombinant Mouse Leptin Protein [E. coli]"){kind=logo}
![Recombinant Mouse Midkine Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671674/929517/logo__42078.1651665136__41957.1651684345.jpg?c=2 "Recombinant Mouse Midkine Protein [E. coli]"){kind=logo}
![Recombinant Mouse MIG Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671678/929521/logo__42078.1651665136__82549.1651684347.jpg?c=2 "Recombinant Mouse MIG Protein [E. coli]"){kind=logo}
![Recombinant Mouse gAcrp30 Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671063/928906/logo__42078.1651665136__68592.1651684165.jpg?c=2 "Recombinant Mouse gAcrp30 Protein [E. coli]"){kind=logo}