Product Description
Recombinant Mouse LIX/CXCL5 (93 aa) Protein [E. coli] | M10-114S/M10-114 | ReliaTech
Species: Mouse
Host / biotech: E. coli
Comment: N/A
Label: N/A
Clone / Antibody feature: N/A
Subcategory: Cytokines & Growth Factors
Category: Recombinant Protein
Synonyms: Cxcl5; LIX; GCP-2; Scyb5; Scyb6; ENA-78; AMCF-II
Isotype: N/A
Application: N/A
Detection Range: Determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/ml.
Species Reactivity/Cross reactivity: Human, Mouse
Antigen: N/A
Description: LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70 amino acid residues, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the ‘ELR’ motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant murine LIX is a 9.8 kDa protein containing 93 amino acid residues.
Purity Confirmation: > 98% by SDS-PAGE & HPLC analyses
Endotoxin: < 0.1 ng/µg of protein (<1EU/µg)
Formulation: lyophilized
Storage Handling Stability: N/A
Reconstituation: N/A
Molecular Weight: 9.8 kDa
Lenght (aa): 93
Protein Sequence: APSSVIAATE LRCVCLTVTP KINPKLIANL EVIPAGPQCP TVEVIAKLKN QKEVCLDPEA PVIKKIIIQK ILGSDKKKAK RNALAVERTA SVQ
NCBI Gene ID: 20311