Product Description
Mouse Anti-Human MMP-10 Antibody | 101-M113 | ReliaTech
Species: Anti-Human
Host / biotech: Mouse
Comment: N/A
Label: N/A
Clone / Antibody feature: (#9G10)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: MMP10; SL-2; STMY2
Isotype: IgG2
Application: WB, IHC (P)
Detection Range: WB: Use at 1:1000; IHC: 1:50-300
Species Reactivity/Cross reactivity: Human
Antigen: recombinant human MMP-10
Description: Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP10 (stromelysin 2) degrades a broad range of substrates including gelatin, collagen types III, IV and V, fibronectin, aggrecan, and pig cartilage proteoglycan. MMP10 can activate other MMPs such as MMP1 and MMP8. MMP10 is expressed in keratinocytes, T cells, menstrual endometrium and a few tumor samples. Structurally, MMP10 may be divided into four distinct domains: a prodomain which is cleaved upon activation, a catalytic domain containing the zinc binding site; a short linker region, and a carboxyl terminal hemopexin- slike domain.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Reconstituation: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 4319