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Product Description
Mouse Anti-Human Podocalyxin Antibody | 101-M142 | ReliaTech
Species: Anti-Human
Host / biotech: Mouse
Comment: N/A
Label: N/A
Clone / Antibody feature: (#GB6D9C11)
Subcategory: Monoclonal Antibody
Category: Antibody
Synonyms: PODXL; PC; PCLP; Gp200; PCLP-1; Podocalyxin-like protein, GCTM-2 antigen, Gp200
Isotype: IgG1
Application: IHC (P); IF
Detection Range: IF/IHC: Use at 2-5 µg/ml.
Species Reactivity/Cross reactivity: Human
Antigen: membrane protein fraction of isolated human glomeruli
Description: Podocalyxin is the major sialoprotein in the glycocalyx of glomerular podocytes. It was shown that endothelial cell membranes contain Podocalyxin. By immunoelectron microscopy Podocalyxin was localized on the luminal membrane domain of endothelial cells, in a patchy distribution. The presence of Podocalyxin was confirmed in SDS extracts of lung tissue by immunoblotting. It is concluded that (a) Podocalyxin is a widespread component of endothelial plasma membranes, (b) it is restricted to the luminal membrane domain, and (c) it is distributed unevenly on the endothelial cell surface.
Purity Confirmation: N/A
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
Reconstituation: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml.
Molecular Weight: N/A
Lenght (aa): N/A
Protein Sequence: N/A
NCBI Gene ID: 5420
