Euro
USD
British Pound
NULL
![Recombinant Human Ephrin-B2, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/670929/928772/logo__42078.1651665136__40831.1651684122.jpg?c=2 "Recombinant Human Ephrin-B2, soluble Protein [E. coli]"){kind=logo}
![Recombinant Human Ephrin-B2, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/670929/928772/logo__42078.1651665136__40831.1651684122.jpg?c=2 "Recombinant Human Ephrin-B2, soluble Protein [E. coli]"){kind=logo}
Product Description
Recombinant Human Ephrin-B2, soluble Protein [E. coli] | S01-068S/S01-068 | ReliaTech
Species: Human
Host / biotech: E. coli
Comment: N/A
Label: His-Tag
Clone / Antibody feature: N/A
Subcategory: Soluble Receptors
Category: Recombinant Protein
Synonyms: EPH-related receptor tyrosine kinase ligand 5; HTK ligand;
Isotype: N/A
Application: N/A
Detection Range: N/A
Species Reactivity/Cross reactivity: Human
Antigen: N/A
Description: The large families of Eph receptor tyrosine kinases and their Ephrin ligands transduce signals in a cell-cell contact-dependent fashion. They thereby coordinate the growth, differentiation, and patterning of almost every organ and tissue. Eph/Ephrin interactions can trigger a wide array of cellular responses, including cell adhesion, boundary formation, and repulsion. The exact mechanisms leading to this diversity of responses are unclear but appear to involve differential signaling, proteolytic cleavage of Ephrins, and endocytosis of the ligand-receptor complex. In the developing cardiovascular system, Eph and Ephrin molecules control the angiogenic remodeling of blood vessels and lymphatic vessels and play essential roles in endothelial cells as well as in supporting pericytes and vascular smooth muscle cells. Recent evidence suggests that Ephs and Ephrins may also be involved in pathological angiogenesis, in particular, the neovascularization of tumors. Consequently, the expression, interactions, or signaling of Eph/Ephrin molecules might be targets for future therapeutic approaches. Ephrins are naturally divided into two structural groups. All ligands share a conserved extracellular sequence, which most likely corresponds to the receptor-binding domain. This conserved sequence consists of approximately 125 amino acids and includes four invariant cysteines. The B-class ligands are transmembrane proteins, which can be tyrosine phosphorylated upon receptor ligation. Class B ephrins show 33% amino acid sequence identity in their extracellular segments and 44% amino acid sequence identity in their cytoplasmic regions.
Purity Confirmation: > 95% by SDS-PAGE
Endotoxin: N/A
Formulation: lyophilized
Storage Handling Stability: N/A
Reconstituation: N/A
Molecular Weight: 23.4 kDa
Lenght (aa): 211
Protein Sequence: MIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDIICPKVDSKTVGQYEYYKVYMVDKDQADRCTIKKENTPLLNCAKPDQDIKFTIKFQEFSPNLWGLEFQKNKDYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNKDPTRRPELEAGTNGRSSTTSPFVKPNPGSSTDGNSAGHSGNNILGSEVALFALEHHHHHH
NCBI Gene ID: 1948
![Recombinant Human Ephrin-B2, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670929/928772/logo__42078.1651665136__40831.1651684122.jpg?c=2 "Recombinant Human Ephrin-B2, soluble Protein [E. coli]"){kind=logo}
![Recombinant Human CD34, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670676/928519/logo__42078.1651665136__94851.1651684060.jpg?c=2 "Recombinant Human CD34, soluble Protein [E. coli]"){kind=logo}
![Recombinant Human CD23, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670656/928499/logo__42078.1651665136__73378.1651684053.jpg?c=2 "Recombinant Human CD23, soluble Protein [E. coli]"){kind=logo}
![Recombinant Human BAFF receptor, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670490/928333/logo__42078.1651665136__82922.1651683813.jpg?c=2 "Recombinant Human BAFF receptor, soluble Protein [E. coli]"){kind=logo}
![Recombinant Human TWEAK receptor, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672207/930050/logo__42078.1651665136__41777.1651684501.jpg?c=2 "Recombinant Human TWEAK receptor, soluble Protein [E. coli]"){kind=logo}
![Recombinant Human Podoplanin, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/671882/929725/logo__42078.1651665136__72782.1651684408.jpg?c=2 "Recombinant Human Podoplanin, soluble Protein [E. coli]"){kind=logo}
![Recombinant Human 4-1BB receptor, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670492/928335/logo__42078.1651665136__47762.1651683814.jpg?c=2 "Recombinant Human 4-1BB receptor, soluble Protein [E. coli]"){kind=logo}
![Recombinant Human FAS receptor, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/670959/928802/logo__42078.1651665136__12980.1651684131.jpg?c=2 "Recombinant Human FAS receptor, soluble Protein [E. coli]"){kind=logo}
![Recombinant Human TRAIL R-1/DR4, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672177/930020/logo__42078.1651665136__26880.1651684494.jpg?c=2 "Recombinant Human TRAIL R-1/DR4, soluble Protein [E. coli]"){kind=logo}
![Recombinant Human TRAIL R-2/DR5, soluble Protein [E. coli]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/672178/930021/logo__42078.1651665136__99769.1651684494.jpg?c=2 "Recombinant Human TRAIL R-2/DR5, soluble Protein [E. coli]"){kind=logo}