Product Description
FGF2 | Basic fibroblast growth factor | IMS01-138-313 | Agrisera
Immunogen: purified full length native protein UniProt:P09038
Host: Chicken
Conjugation: N/A
Clonality: Polyclonal
Isotype: N/A
Purity: Purified, total IgY (chicken egg yolk immunoglobulin) in 0.9% NaCl, 0.02% sodium azide.
Format: Liquid
Tested Application: Total, purified IgY
Related Products: N/A
Recommended Dilutions: 1 : 1000 (ELISA), 1 : 1000 (WB)
Molecular weight: 18 kDa
Confirmed Reactivity: Human
Predicted Reactivity: Bovine, Chicken, Mouse, Rat, Sheep
Not reactive in: No confirmed exceptions from predicted reactivity are currently known
Additional Information: Reacts with human recombinant FGF2, No reactivity with other human serum proteins
Background: Basic Fibroblast Growth Factor (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Reconstitution: N/A
Storage: Store at 4°C; make aliquots to avoid working with a stock. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
TAIR Nnumbre: N/A
Category: Cancer
Research Area: Cancer Research