Product Description
Abeta (1-42) | Amyloid-beta peptide 1-42 | AS08 328 | Agrisera
Immunogen: synthetic peptide chosen from human Abeta (1-42) protein, Amino acid sequence: D-A-E-F-R-H-D-S-G-Y-E-V-H-H-Q-K-L-V-F-F-A-E-D-V-G-S-N-K-G-A-I-I-G-L-M-V-G-G-V-V-I-A
Host: Rabbit
Conjugation: N/A
Clonality: Polyclonal
Isotype: N/A
Purity: Serum
Format: Lyophilized
Tested Application: Dot Blot (Dot), ELISA (ELISA), Immunolocalization (IL), Western blot (WB)
Related Products: Alzheimer | available antibodies for Alzheimer's disease
Recommended Dilutions: 1 : 1000 (DB), 1 : 3000 (ELISA), 1-2 µg/ml (IL)
Molecular weight: 4, 5 kDa
Confirmed Reactivity: Human
Predicted Reactivity: Bovine, Chicken, Dog, Porcine, Rabbit
Not reactive in: No confirmed exceptions from predicted reactivity are currently known
Additional Information: The antibody can detect Abeta (1-42), Abeta (1-28) Abeta (1-20) and Abeta (1-17), This product exhibits a low reactivity to monomeric Abeta (1-42) as determined by SDS-PAGE and Western blotting, Immunolocalization: human tissue was paraffin-embedded and sectioned, De-waxed and rehydrated in an ethanol gradient, Antigens were retrieved in sodium citrate buffer (pH 6) at 95°C for 1 h, The tissue sections were separately incubated for 1 h at RT with primary antibody and antibody binding was visualized with IgG Preoxidase Reagent Kit
Background: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease in the growing population of elderly people. A hallmark of AD is the accumulation of plaques in the brain of AD patients. The plaques predominantly consist of aggregates of amyloid-beta (Abeta), a peptide of 39-42 amino acids generated in vivo by specific, proteolytic cleavage of the amyloid precursor protein P05067
Reconstitution: For reconstitution add 100 µl of sterile water
Storage: Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
TAIR Nnumbre: N/A
Category: Alzheimer's disease
Research Area: Pathology