Product Description
Fas-associating death domain containing protein (FADD), also known as mediator of receptor induced toxicity (MORT1), is a 23 kDa cytosolic protein with an apparent molecular weight of 28 kDa on SDS-PAGE. The protein is involved in both Fas and TNF-R induced cell death pathway. FADD specifically binds to Fas to initiate the apoptotic signalling cascade. Overexpression of FADD induces apoptosis.
Biovision | 3039 | FADD Antibody DataSheet
Antibody Target: FADD
Target Alternative Name: FAS-associated death domain protein, GIG3, mgC8528, MORT1
Tag Line:
Category: FADD
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human, mouse, rat, monkey
Immunogen Sequence: Synthetic peptide surrounding amino acid 128 of human FADD
Accession #: Q13158
Gene ID: 8772
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.2 mg/ml
Formulation: 30 µg (0.2 mg/ml) affinity purified rabbit anti-FADD polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.
Purification: Affinity purified
Application: Western blot, Immunoprecipitation
Positive Control:
Application And Usages: Western blot analysis (0.5-4 µg/ml)and can also be used in immunoprecipitation. However, the optimal conditions should be determined individually. The antibody detects an ~28 kDa band, corresponding to the expected molecular mass of FADD on immunoblots.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified: Not Verified
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified: Not Verified
Flow Cytometry Verified: Not Verified