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Product Description
RGS3 (regulator of G protein signaling 3) is a 519-residue protein that is widely expressed in many tissues and cells. The protein contains an RGS domain near the carboxy terminus that serves as a GTPase-activating protein (GAP). RGS3 negatively regulates the activation of Gi? and G?q. A truncated RGS3 (RGS3T), with its N-terminal 313 residues removed, has been shown to negatively regulate acenylyl cyclase and PLC. RGS3T may be localized in the nucleus and RGS3 is found in cytoplasm. Translocation to membrane is important for the RGS proteins to interact with heterotrimeric G proteins.
Biovision | 3280 | RGS3 Antibody DataSheet
Antibody Target: RGS3
Target Alternative Name: RGS3, 602189, P49796, C2PA, FLJ20370, FLJ31516, FLJ90496, PDZ-RGS3, RGP3
Tag Line:
Category: RGS3
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human
Immunogen Sequence: E. coli-expressed human RGS3
Accession #: P49796
Gene ID: 5998
Appearance: Colorless liquid
Form: Liquid
Concentration: 0.2 mg/ml
Formulation: 100 µg (0.2 mg/ml) protein A-purified rabbit anti-RGS3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% sodium azide.
Purification: Affinity purified
Application: Western blot, Immunoprecipitation
Positive Control:
Application And Usages: Western blot analysis (1 µg/ml) and immunoprecipitation. However, the optimal conditions should be determined individually.
Country of Animal Origin: China
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Verified
Immunocytochemistry Verified: Not Verified
Immunofluorescence Verified: Not Verified
Immunoprecipitation Verified: Not Verified
FACS Verified:
ELISA Verified: Not Verified
ChIP Verified: Not Verified
Dot Blot Verified:
Flow Cytometry Verified: Not Verified
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