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Product Description
Rabbit Anti-Human AKT1 Polyclonal
Product Videos
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Size 100 µg
Target AKT1
Conjugate APC/Cy7
Research Area Cell Signaling, Protein Phosphorylation, Serine / Threonine Kinases, PKB / AKT, Cell Signaling, Metabolism, Metabolism processes, Cell Signaling, Epigenetics and Nuclear Signaling, Cancer, Apoptosis, Cell Signaling, Metabolism, Metabolism processes
Alternative Name RAC-alpha serine/threonine-protein kinase Antibody, Protein Kinase B Alpha Antibody, EC:2.7.11.1 Antibody, AKT1 Antibody, AKT Antibody, MGC99656 Antibody, PKB alpha Antibody, PKB-ALPHA Antibody, AKT 1 Antibody, RAC-PK-alpha Antibody, PRKBA Antibody,
Category Antibodies
Product Type Polyclonal
Immunogen Synthetic peptide from the mid-protein of Human AKT1 (aa. 100-200)
Immunogen Species Human
Applications WB, IHC
Isotype NA
Species Reactivity Human, Mouse
Antibody Dilution WB (1:1000); IHC (1:50); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Storage Buffer PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Concentration 1 mg/ml
Specificity Detects 65 kDa. Band is detected at ~65 kDa, due to post translational modifications.
Storage -20ºC
Shipping Blue Ice or 4ºC
Certificate of Analysis A 1:1000 dilution of SPC-768 was sufficient for detection of AKT1 in 15 µg of mouse Brain cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cellular Localization Cytoplasm, Nucleus, Cell Membrane
Accession Number NP_001014431.1
Gene ID 207
Swiss-Prot P31749
Tissue Specificity Expressed in prostate cancer and levels increase from the normal to the malignant state (at protein level). Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancer
