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Product Description
Rabbit Anti-Human IKK alpha + IKK beta (pSer176/177) Polyclonal
Product Videos
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Size 100 µl
Target IKK alpha + IKK beta (pSer176/177)
Conjugate FITC
Research Area Cell Signaling | Protein Phosphorylation | Serine / Threonine Kinases | Cell Signaling | Epigenetics and Nuclear Signaling | Nuclear Signaling Pathways | NFkB Pathway | IKK | Cardiovascular System | Atherosclerosis | Vascular Inflammation | Inflammat
Alternative Name IKKA Antibody, IKKB Antibody, CHUK Antibody, IKKα/β Antibody, Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor Antibody, Inhibitor Of Nuclear Factor Kappa B Kinase Alpha Subunit Antibody, I Kappa B Kinase 1 Antibody, TCF16 Antib
Category Antibodies
Product Type Polyclonal Antibody
Immunogen Synthetic phospho-peptide from human IKK alpha + IKK beta proteins around the phosphorylation sites of IKKα at serine 176 (pSer176) and IKKβ at serine 177 (pSer177).
Immunogen Species Human
Applications WB, IHC, ELISA
Host Rabbit
Isotype N/A
Species Reactivity Human, Mouse, Rat
Antibody Dilution WB (1:250-1:1000); IHC (1:50-1:150); ELISA (1:5000); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Storage Buffer PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide
Concentration N/A
Specificity Detects endogenous levels of IKKα only when phosphorylated at serine 176 (pSer176) and IKKβ only when phosphorylated at serine 177 (pSer177). Detects a band at ~80 kDa.
Storage -20ºC
Shipping Blue Ice or 4ºC
Certificate of Analysis N/A
Cellular Localization Nucleus, Cytoplasm, Cytosol, Ikappab Kinase Complex, Nucleoplasm, Plasma Membrane, Cd40 Receptor Complex, Cytoplasmic Side Of Plasma Membrane, Intracellular Membrane-Bounded Organelle, Membrane Raft
Tissue Specificity Alpha: Widely expressed. Beta: Highly expressed in heart, placenta, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis and peripheral blood.
Accession Number NP_001269.3/NP_001177649.1
Gene ID 1147/3551
Swiss-Prot O15111/O14920
Field of Use For in vitro research use only.
