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Product Description
Rabbit Anti-Human LGR5 Polyclonal
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Size 100 µg
Target LGR5
Conjugate PerCP
Research Area Cell Signaling | G Protein Signaling | GPCR | Stem Cells | Signaling Pathways | Wnt / Beta Catenin Pathway
Alternative Name GPR49 Antibody, G-protein coupled receptor 67 Antibody, G-protein coupled receptor HG38 Antibody, Leucine-rich repeat-containing G-protein coupled receptor 5 Antibody, LGR5 Antibody, G-protein coupled receptor 49 Antibody, GPR67 Antibody, GPCR GPR49
Category Antibodies
Product Type Polyclonal Antibody
Immunogen Synthetic peptide from the mid-protein of Human LGR5 (aa. 500-600)
Immunogen Species Human
Applications WB
Host Rabbit
Isotype N/A
Species Reactivity Human
Antibody Dilution WB (1:1000); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Storage Buffer PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Concentration 1 mg/ml
Specificity Detects 97 kDa. Band at ~97 kDa in isoform 2. Band at ~70 kDa is a degradation product..
Storage -20ºC
Shipping Blue Ice or 4ºC
Certificate of Analysis A 1:1000 dilution of SPC-764 was sufficient for detection of LGR5 in 10 µg of human HeLa cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cellular Localization Cell Membrane, Multi-Pass Membrane Protein, Golgi Apparatus, Trans-Golgi Network Membrane, Multi-Pass Membrane Protein
Tissue Specificity Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers
Accession Number NP_001264155.1
Gene ID 8549
Swiss-Prot O75473
Field of Use For in vitro research use only.
