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Product Description
Rabbit Anti-Human MDM2 Polyclonal
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Size 100 µg
Target MDM2
Conjugate ATTO 633
Research Area Cancer, Cell Cycle, p53 Pathway, Cell Signaling, Epigenetics and Nuclear Signaling, Cancer, Tumor Biomarkers, Oncoproteins
Alternative Name Double minute 2 protein Antibody, Hdm2 Antibody, MTBP Antibody, Mouse Double Minute 2 Antibody, HDMX Antibody, ACTFS Antibody, p53 Binding Protein Mdm2 Antibody, Ubiquitin protein ligase E3 Mdm2 Antibody, Mdm2 p53 E3 ubiquitin protein ligase homolog
Category Antibodies
Product Type Polyclonal
Immunogen Synthetic peptide from the mid-protein of Human MDM2 (aa. 100-200)
Immunogen Species Human
Applications WB, IHC
Isotype NA
Species Reactivity Human, Mouse, Rat
Antibody Dilution WB (1:1000); IHC (1:50); optimal dilutions for assays should be determined by the user.
Purification Peptide Affinity Purified
Storage Buffer PBS pH 7.4, 50% glycerol, 0.09% Sodium Azide
Concentration 1 mg/ml
Specificity Detects ~50 kDa. ~50 kDa band is isoform 2 or 3.
Storage -20ºC
Shipping Blue Ice or 4ºC
Certificate of Analysis A 1:1000 dilution of SPC-777 was sufficient for detection of KRAS in 15 µg of rat Kidney cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
Cellular Localization Nucleus, Nucleoplasm, Cytoplasm, Nucleus, Nucleolus
Accession Number NP_001138811.1
Gene ID 4193
Swiss-Prot Q00987
Tissue Specificity Ubiquitous. Isoform Mdm2-A, isoform Mdm2-B, isoform Mdm2-C, isoform Mdm2-D, isoform Mdm2-E, isoform Mdm2-F and isoform Mdm2-G are observed in a range of cancers but absent in normal tissues.
