Product Description
Hepatitis C virus (HCV) is a positive, single-stranded RNA virus in the Flaviviridae family. The HCV core protein represents the first 191 amino acids of the viral precursor polyprotein. Polymerization of the HCV core protein forms the virus capsid, which houses its RNA genome. HCV is the cause of chronic hepatitis, liver cirrhosis, and some cancers in humans through blood and body fluid transmission. After translation, signal peptidases of the host cleave the precursor polyprotein and remove the signal peptide, which generates the HCV core protein antigen (HCVcAg). Its primary sequence is the most conserved sequence among the HCV proteins, making it a potential protein marker for HCV infection. The HCV core protein has been previously shown to circulate in the bloodstream of HCV-infected patients, therefore it serves as a well-developed marker for the diagnosis of infection.
Biovision | A2357 | Anti-Hepatitis C Virus Core Antigen Monoclonal Antibody (C8) DataSheet
Antibody Target: Hepatitis C Virus Core Antigen
Target Alternative Name: Core protein p21 antibody, HCV core antigen antibody, HCV core protein antibody, Hepatitis C Virus core protein antibody
Tag Line: Monoclonal antibody targeting a key diagnostic marker for Hepatitis C
Category: GM-CSF
Host: HEK 293 cells
Isotype: Mouse IgG2 kappa
Species Reactivities: Hepatitis C Virus
Immunogen Sequence: Epitope within amino acids 1-50 of HCVcAg
Accession #:
Gene ID:
Appearance: Liquid
Form: Mouse monoclonal
Concentration:
Formulation: In PBS with 1% BSA, 0.5 mM EDTA, 30% glycerol, and 0.03% Proclin
Purification: Protein A Purification
Application: ELISA
Positive Control:
Application And Usages:
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: TRUE
Immunocytochemistry Verified: FALSE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE