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Product Description
MART-1 (also known as Melan-A) is a melanocyte differentiation antigen or marker recognized by autologous cytotoxic T lymphocytes. It is a membrane protein with one transmembrane peptide. Melan-A is expressed by a large proportion of melanoma tumors, both melanotic and amelanotic and by melanoma cell lines. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. Melan-A/MART-1 is not expressed by non-melanoma malignancies. It is recognized by autologous cytotoxic T lymphocytes. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1.
Biovision | A1845 | Anti-MART1 Rabbit Monoclonal Antibody (RM333) DataSheet
Antibody Target: MART-1 (Melanoma antigen recognized by T-cells 1)
Target Alternative Name:
Tag Line: Affinity purified Rabbit monoclonal to MART1
Category: Primary antibody
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human
Immunogen Sequence: A peptide corresponding to the N-terminus of human MART1 (Melanoma antigen recognized by T-cells-1).
Accession #: Q16655
Gene ID: 2315
Appearance: Liquid
Form: Liquid
Concentration:
Formulation: 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification: Protein A affinity purified from an animal originfree culture supernatant
Application: Western Blot: 1:500-1:1000, IHC: 1:500-1:1000
Positive Control:
Application And Usages: Western Blot: 1:500-1:1000, IHC: 1:500-1:1000
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: True
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
