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Product Description
Stathmin (STMN1), a member of the stathmin family, is also known as Leukemia-associated phosphoprotein p18, Oncoprotein 18 (Op18), Phosphoprotein p19 (pp19), Protein Pr22 and pp17, which contains one SLD (stathmin-like) domain. The function of STMN1 as an important regulatory protein of microtubule dynamics has been well-characterized. Stathmin (STMN1) interacts with two molecules of dimeric ?,?-tubulin to form a tight ternary complex called the T2S complex.One mole of STMN1 binds to two moles of tubulin dimers through the stathmin-like domain (SLD).When STMN1 sequesters tubulin into the T2S complex, tubulin becomes non-polymerizable. Without tubulin polymerization, there is no microtubule assembly.STMN1 also promotes microtubule disassembly by acting directly on the microtubule ends.
Biovision | A1856 | Anti-Stathmin (STMN1) Rabbit Monoclonal Antibody (RM350) DataSheet
Antibody Target: Stathmin (STMN1)
Target Alternative Name:
Tag Line: Affinity purified Rabbit monoclonal to Stathmin (STMN1)
Category: Primary antibody
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human
Immunogen Sequence: A peptide corresponding to C-terminus of human Stathmin
Accession #: P16949
Gene ID: 3925
Appearance: Liquid
Form: Liquid
Concentration:
Formulation: 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Purification: Protein A affinity purified from an animal originfree culture supernatant
Application: Western Blot: 1:2000-1:5000, IHC: 1:500-1:1000
Positive Control:
Application And Usages: Western Blot: 1:2000-1:5000, IHC: 1:500-1:1000
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: True
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False
