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Product Description
Fibrinogen is a glycoprotein complex composed of three different polypeptides (?, ?, ?) that is cleaved by thrombin to form an insoluble fibrin matrix that acts as a plasma clotting factor. Cleavage products of fibrinogen and fibrin regulate cell adhesion and activate chemotaxis. Chronic inflammation can induce protein arginine deiminases (such as PAD2 and PAD4) to citrullinate fibrinogen, which has been associated with auto-antibodies in rheumatoid arthritis.
Biovision | A2316 | Citrullinated Fibrinogen Monoclonal Antibody (Clone 10E9.3) DataSheet
Antibody Target: Human citrullinated fibrinogen
Target Alternative Name: Fibrinogen Alpha Chain; Fibrinogen, A Alpha Polypeptide; Fib2; FGA; Fibrinogen Beta Chain; Fibrinogen, B Beta Polypeptide; Epididymis Secretory Sperm Binding Protein Li 78p; Beta-Fibrinogen; HEL-S-78p; FGB; Fibrinogen Gamma Chain; Fibrinogen, Gamma Polypeptide; Testicular Tissue Protein Li 70; FGG
Tag Line: A critical factor in blood clotting, inflammation, and rheumatoid arthritis
Category: GM-CSF
Host: Mouse
Isotype: Mouse IgG2b
Species Reactivities: Human
Immunogen Sequence: Human citrullinated fibrinogen
Accession #: P02675
Gene ID: 2244
Appearance: Liquid
Form:
Concentration:
Formulation: PBS, pH 7.2, with 50% glycerol and 0.02% sodium azide
Purification: Protein G purification
Application: Western Blotting ELISA
Positive Control:
Application And Usages:
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: TRUE
Immunocytochemistry Verified: TRUE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
