Product Description
The KLRB1 protein, also known as CD161, is expressed by natural killer cells and is involved in the regulation of NK cell function. Certain subpopulations of T cells also express CD161 on their surface. CD161 inhibits NK cell cytotoxicity, and T cells that express CD161 may be linked to inflammation and immunological disorders. Expression of CD161 on T cells has been linked to glioma and other human cancer types. Inactivation of CD161 has been shown recently to mediate the killing of glioma cells and exact anti-tumor functions, making it an intriguing therapeutic target.
Biovision | A2309 | Anti-CD161/KLRB1 Antibody DataSheet
Antibody Target: Human CD161/KLRB1
Target Alternative Name: Killer Cell Lectin Like Receptor B1; Natural Killer Cell Surface Protein P1A; NKR-P1A; CLEC5B; Killer Cell Lectin-Like Receptor Subfamily B Member 1; C-Type Lectin Domain Family 5 Member B; HNKR-P1A; NKR-P1; NKRP1A; CD161 Antigen; KLRB1; NKR
Tag Line: Plays an inhibitory role on natural killer cell cytotoxicity
Category: GM-CSF
Host: Rabbit
Isotype: IgG
Species Reactivities: Human Mouse
Immunogen Sequence: Fusion protein of Human KLRB1
Accession #: Q12918
Gene ID: 3820
Appearance: Liquid
Form: Rabbit polyclonal
Concentration:
Formulation: In PBS pH 7.4, 0.05% sodium azide, 40% glycerol
Purification: Antigen affinity purification
Application: ELISA Western Blotting Immunohistochemistry (IHC)
Positive Control:
Application And Usages:
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: TRUE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: TRUE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE