Product Description
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
Biovision | A1910 | Anti-CD44 Antibody DataSheet
Antibody Target: CD44
Target Alternative Name: MC56, LHR, HCELL, CD44 antigen, Pgp1, ECMR-III, MIC4, MDU2, CDW44, CD44, HUTCH-I, IN, CSPG8, MDU3
Tag Line: Affinity purified Rabbit polyclonal to CD44
Category: Primary antibody
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Mouse, Human
Immunogen Sequence: Recombinant fusion protein containing a sequence corresponding to amino acids 35-300 of human CD44 (NP_001001389.1).
Accession #: P16070
Gene ID: 960
Appearance: Liquid
Form: Liquid
Concentration:
Formulation: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification:
Application: Immunohistochemistry (IHC), Western Blotting
Positive Control:
Application And Usages: IHC 1:50 - 1:200, WB 1:500 - 1:2000
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: True
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False