Euro
USD
British Pound
NULL
Product Description
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack poly A tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
Biovision | A2031 | Anti-H3K36me3 Antibody DataSheet
Antibody Target: H3K36me3
Target Alternative Name: H3.4; H3/g; H3FT; H3t; HIST3H3; Histone H3; HIST1H3A
Tag Line: Affinity purified rabbit polyclonal antibody to detect trimethylation of Histone H3 at Lysine 36 in human, mouse and rat samples
Category: Antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Rat, Mouse, Human
Immunogen Sequence: A synthetic methylated peptide targeting residues around Lysine 36 of human Histone H3
Accession #: Q16695
Gene ID: 8290
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification: Affinity purified
Application: ChiP, Immunohistochemistry (IHC), Immunofluorescence (IF), Dot Blot, Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200, ChIP 1:20 - 1:100
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: Western blot data verified using HeLa, C2C12 cells and H3 protein extracts
Immunocytochemistry Verified: True
Immunofluorescence Verified: True
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: True
Dot Blot Verified: True
Flow Cytometry Verified: False
