Product Description
Protein arginine deiminases (PADs) are a family of guanidine-modifying enzymes that catalyze the post-translational modification of target proteins by converting arginine to citrulline. Excessive citrullination of proteins may result in disease states. PAD6 is primarily expressed in mammalian oocytes, sperm cells, and early embryoes. PAD6 may have a role in regulating microtubule-mediated organelle mobility and positioning within cells, and cytoskeletal reorganization in the egg and early embryo. Dysregulation of PAD6 is associated with embryonic lethality.
Biovision | A2325 | Anti-PAD6 Polyclonal Antibody DataSheet
Antibody Target: Human PAD6
Target Alternative Name: Peptidyl Arginine Deiminase 6; Peptidyl Arginine Deiminase-Like Protein; Peptidyl Arginine Deiminase, Type VI; Protein-Arginine Deiminase Type-6; EC 3.5.3.15; HPADVI; Protein-Arginine Deiminase Type VI; Peptidylarginine Deiminase Type 6; Peptidylarginine Deiminase VI; PREMBL2; PADI6
Tag Line: Protein arginine deiminase associated with embryonic development
Category: GM-CSF
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Mouse Human
Immunogen Sequence: KLH conjugated synthetic peptide of human PAD6 (amino acids 196 to 223)
Accession #: Q6TGC4
Gene ID: 353238
Appearance: Liquid
Form: Rabbit polyclonal
Concentration:
Formulation: In PBS with 0.09% (W/V) sodium azide
Purification: Protein A purification, followed by peptide affinity purification
Application: Western Blotting
Positive Control:
Application And Usages:
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: TRUE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE