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Product Description
The Aurora family of serine/threonine kinases is involved in the regulation of cell cycle progression. Aurora kinases regulate chromosome alignment and segregation during mitosis and meiosis through the formation and stabilization of microtubules at centrosomes and spindle poles. Aberrant expression of Aurora kinases is associated with several cancer cell lines, suggesting a role in tumor development and progression.
Antibody Target: Human Aurora Kinase phosphorylated at T288 (AURKA), T232 (AURKB), T198 (AURKC)
Target Alternative Name: Aurora Kinase A; Aurora Kinase B; Aurora Kinase C; ARK1; ARK2; ARK3
Tag Line: Regulates chromosome alignment and segregation during mitosis and meiosis
Category: GM-CSF
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human
Immunogen Sequence: A phospho specific peptide corresponding to residues surrounding T288/T232/T198 of human AURKA/AURKB/AURKC.
Accession #: AURKA - O14965; AURKB - Q96GD4; AURKC - Q9UQB9
Gene ID: AURKA - 6790; AURKB - 9212; AURKC - 6795
Appearance: Liquid
Form: Rabbit polyclonal
Concentration:
Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification: Affinity purification
Application: Western Blotting
Positive Control:
Application And Usages: Western Blotting
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: TRUE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
