Product Description
This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Biovision | A1918 | Anti-SIM2 Antibody DataSheet
Antibody Target: SIM2
Target Alternative Name: HMC13F06, HMC29C01, SIM2, single-minded homolog 2, bHLHe15, SIM
Tag Line: Affinity purified Rabbit polyclonal to SIM2
Category: Primary Antibodies
Host: Rabbit
Isotype: Rabbit IgG
Species Reactivities: Human
Immunogen Sequence: Recombinant fusion protein containing a sequence corresponding to amino acids 342-525 of human SIM2 (NP_033664.2).
Accession #: Q14190
Gene ID: 6493
Appearance: Liquid
Form: Liquid
Concentration:
Formulation: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification: Affinity purification
Application: Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:2000
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: False
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False