Product Description
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multi-subunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Biovision | A1945 | Phospho EIF4EBP1 (Thr36) Antibody DataSheet
Antibody Target: Phospho EIF4EBP1 (Thr36)
Target Alternative Name: EIF4EBP1; 4E-BP1; 4EBP1; BP-1; PHAS-I; eukaryotic translation initiation factor 4E-binding protein 1
Tag Line: Affinity purified rabbit polyclonal antibody to detect phosphorylation of EIF4EBP1 at Thr36 in human, mouse and rat samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Rat, Mouse, Human
Immunogen Sequence: A phospho specific peptide corresponding to residues surrounding Thr36 of human EIF4EBP1
Accession #: Q13541
Gene ID: 1978
Appearance: Liquid
Form: Liquid
Concentration:
Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Purification: Affinity purified
Application: Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:2000
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: False
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False