Product Description
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
Biovision | A1958 | Phospho PFKFB2 (Ser483) Antibody DataSheet
Antibody Target: Phospho PFKFB2 (Ser483)
Target Alternative Name: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme
Tag Line: Affinity purified rabbit polyclonal antibody to detect phosphorylation of PFKFB2 at Ser483 in human, mouse, rat and bovine samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Bovine, Rat, Mouse, Human
Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human PFKFB2.
Accession #: O60825
Gene ID: 5208
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification: Affinity purified
Application: Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:1000
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: False
Immunofluorescence Verified: False
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False