Product Description
Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.
Biovision | A1959 | Phospho TSC2 (Thr1462) Antibody DataSheet
Antibody Target: Phospho TSC2 (Thr1462)
Target Alternative Name: TSC4; Tuberin; Tuberous sclerosis 2 protein, LAM; PPP1R160
Tag Line: Affinity purified rabbit polyclonal antibody to detect phosphorylation of TSC2 at Thr1462 in human, mouse, rat and monkey samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Rat, Monkey, Mouse, Human
Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human TSC2
Accession #: P49815
Gene ID: 7249
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
Purification: Affinity purified
Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:1000), IHC 1:100 - 1:200, IF 1:100 - 1:500
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: True
Immunocytochemistry Verified: True
Immunofluorescence Verified: True
Immunoprecipitation Verified: False
FACS Verified: False
ELISA Verified: False
ChIP Verified: False
Dot Blot Verified: False
Flow Cytometry Verified: False