Product Description
Biovision | XL-147 | B3352
Description: XL-147 is a potent and reversible Class 1 PI3-kinase family inhibitor with potential antineoplastic activity. Inactivation of PI3K has been shown to inhibit growth and induce apoptosis (programmed cell death) in tumor cells.
Alternate Name/Synonyms: SAR245408 Pilaralisib 2-amino-N-[3-[[[3-[(2-chloro-5-methoxyphenyl)amino]-2-quinoxalinyl]amino]sulfonyl]phenyl]-2-methyl-propanamide
Appearance: Solid
Formulation:
CAS Number: 934526-89-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₅H₂₅ClN₆O₄S
Molecular Weight: 541.02
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: >40 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Tag Line: A PI3K inhibitor
PubChem CID: 56599306
PubChem CID Link: https://pubchem.ncbi.nlm.nih.gov/compound/56599306
SMILES: CC(C)(C(=O)NC1=CC(=CC=C1)S(=O)(=O)NC2=NC3=CC=CC=C3N=C2NC4=C(C=CC(=C4)OC)Cl)N
InChi: InChI=1S/C25H25ClN6O4S/c1-25(2,27)24(33)28-15-7-6-8-17(13-15)37(34,35)32-23-22(29-19-9-4-5-10-20(19)30-23)31-21-14-16(36-3)11-12-18(21)26/h4-14H,27H2,1-3H3,(H,28,33)(H,29,31)(H,30,32)
InChi Key: QINPEPAQOBZPOF-UHFFFAOYSA-N
Category: Biochemicals