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Product Description
Biovision | Anti-Phospho-BRCA1 (S1423) Polyclonal Antibody | A2360
Description: The BRCA1 protein is an E3 ubiquitin ligase that plays a central role in DNA repair and has tumor suppressor functions. Among other functions, BRCA1 coordinates DNA repair, cell cycle arrests triggered by ionizing radiation, and transcriptional regulation of other genes involved in DNA repair and maintenance. Mutations in BRCA1 are observed in approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers.
Antibody Target: Human BRCA1 phosphorylated at serine 1423
Target Alternative Name: BRCA1; BRCAI; BRCC1; BROVCA1; FANCS; IRIS; PNCA4; PPP1R53; PSCP; RNF53
Tag Line: Critical tumor suppressor that maintains genomic stability
Category: GM-CSF
Lot #:
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Clone#:
Species Reactivities: Rat, Human
Immunogen Sequence: A synthetic phosphorylated peptide around serine 1423 of human BRCA1
Accession #: P38398
Gene Id: 672
Form: Liquid
Appearance: Rabbit polyclonal
Concentration:
Formulation: In PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
Purification: Affinity purification
Application: Immunofluorescence (IF) Immunohistochemistry (IHC) Western Blotting
Positive Control: Immunofluorescence (IF) Immunohistochemistry (IHC) Western Blotting
Application And Usages:
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: TRUE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: TRUE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: TRUE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
