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Product Description
Biovision | IL-21 (Human) ELISA Kit | E5052-100
Description: Interleukin-21 (IL-21) is a cytokine with broad pleiotropic actions that affect the differentiation and function of lymphoid and myeloid cells. IL-21 regulates both innate and adaptive immune responses and also exerts major effects on inflammatory responses that promote the development of autoimmune diseases and inflammatory disorders. IL-21 is expressed in activated human CD4+ T cells but not in most other tissues. In addition, IL-21 expression is up-regulated in Th2 and Th17 subsets of T helper cells, as well as T follicular cells. Regulation of the expression levels of IL-21 and IL-21R and blocking of their signal transduction pathways with blockers may be new treatment options for autoimmune diseases. BioVision’s IL-21 (Human) ELISA Kit is used for the quantitative detection of IL-21 in serum, plasma, tissue homogenates and other biological fluids. It is based on the principle of sandwich ELISA. The capture antibody is pre-coat on 96-well plates. The standards, test samples and biotin conjugated detection antibody are added to the wells subsequently, and washed with wash buffer. HRP-Streptavidin is added and unbound conjugates are washed away with wash buffer. The HRP enzymatic reaction is detected using TMB-substrate. Finally, an acidic stop solution terminates the enzymatic reaction. The color developed is directly proportional to the amount of IL-21 in the sample.
Alternate Name: IL-21 ELISA Kit; Interleukin-21 ELISA Kit; Za11 ELISA Kit; IL21 ELISA Kit; CVID11 ELISA Kit
Tag Line: A highly sensitive ELISA kit for the quantitative measurement of IL-21
Summary: N/A
Detection Method: Absorbance is measured at 450 nm
Sample Type: Human Serum, Plasma, Tissue lysates and other biological fluids
Species Reactivity: Human
Applications: The ELISA kit is used for the quantitative detection of IL-21 in serum, plasma, tissue homogenates and other biological fluids
Features & Benefits: Assay Precision; Intra-Assay CV < 8% and Inter-Assay < 10% Recovery Rate: 88-98% for Serum, 88-104% for EDTA plasma and 89-96% for Heparin plasma Highly sensitive and specific Detection range: 62.5-4000 pg/ml Sensitivity: 37.5 pg/ml
